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GNRHR 抗体 (AA 41-90)

This 兔 多克隆 antibody specifically detects GNRHR in WB, IF 和 ELISA. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN1535695
发货至: 中国
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Quick Overview for GNRHR 抗体 (AA 41-90) (ABIN1535695)

抗原

See all GNRHR 抗体
GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

适用

  • 74
  • 19
  • 14
  • 1
人, 小鼠

宿主

  • 44
  • 34
  • 1
兔

克隆类型

  • 45
  • 34
多克隆

标记

  • 42
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GNRHR antibody is un-conjugated

应用范围

  • 33
  • 29
  • 27
  • 19
  • 14
  • 9
  • 8
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), ELISA
  • 抗原表位

    • 32
    • 28
    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 41-90

    原理

    GnRH-R Antibody

    特异性

    GnRH-R Polyclonal Antibody detects endogenous levels of GnRH-R protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human GNRHR. AA range:41-90

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

    别名

    GNRHR

    背景

    Synonyms: GNRHR; GRHR; Gonadotropin-releasing hormone receptor; GnRH receptor; GnRH-R

    Background: This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gen

    Gene Name: GNRHR

    Protein Name: Gonadotropin-releasing hormone receptor

    分子量

    37 kDa

    基因ID

    2798

    OMIM

    138850

    UniProt

    P30968
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