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GALR2 抗体 (AA 201-250)

The 兔 多克隆 anti-GALR2 antibody (ABIN1535690) specifically detects GALR2 in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1535690
发货至: 中国
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Quick Overview for GALR2 抗体 (AA 201-250) (ABIN1535690)

抗原

See all GALR2 抗体
GALR2 (Galanin Receptor 2 (GALR2))

适用

  • 43
  • 13
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  • 1
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人, 小鼠, 大鼠

宿主

  • 44
  • 1
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兔

克隆类型

  • 45
  • 1
多克隆

标记

  • 19
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  • 1
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This GALR2 antibody is un-conjugated

应用范围

  • 33
  • 17
  • 14
  • 14
  • 8
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  • 5
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 16
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    AA 201-250

    原理

    GALR2 Antibody

    特异性

    GALR2 Polyclonal Antibody detects endogenous levels of GALR2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human GALR2. AA range:201-250

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    GALR2 (Galanin Receptor 2 (GALR2))

    别名

    GALR2

    背景

    Synonyms: GALR2, GALNR2, Galanin receptor type 2, GAL2-R, GALR-2

    Background: Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simul

    Gene Name: GALR2

    Protein Name: Galanin receptor type 2

    分子量

    41 kDa

    基因ID

    8811

    OMIM

    603691

    UniProt

    O43603

    途径

    cAMP Metabolic Process, Inositol Metabolic Process, Feeding Behaviour
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