GABBR1 抗体 (AA 891-940)
Our Local Distributor
北京 101111
Quick Overview for GABBR1 抗体 (AA 891-940) (ABIN1535688)
抗原
See all GABBR1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 891-940
-
原理
- GABAB R1 Antibody
-
特异性
- GABAB R1 Polyclonal Antibody detects endogenous levels of GABAB R1 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human GABBR1. AA range:891-940
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
-
: "Oligomerization of the heteromeric γ-aminobutyric acid receptor GABAB in a eukaryotic cell-free system." in: Scientific reports, Vol. 12, Issue 1, pp. 20742, (2022) (PubMed).
-
-
- GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))
-
别名
- GABBR1
-
背景
-
Synonyms: GABBR1, GPRC3A, Gamma-aminobutyric acid type B receptor subunit 1, GABA-B receptor 1, GABA-B-R1, GABA-BR1, GABABR1, Gb1
Background: This gene encodes a receptor for gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. This receptor functions as a heterodimer with GABA(B) receptor 2. Defects in this gene may underlie brain disorders such as schizophrenia and epilepsy. Alternative splicing generates multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jan 2016],
Gene Name: GABBR1
Protein Name: Gamma-aminobutyric acid type B receptor subunit 1
-
分子量
- 108 kDa
-
基因ID
- 2550
-
OMIM
- 603540
-
UniProt
- Q9UBS5
-
途径
- Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process
抗原
-