Muscarinic Acetylcholine Receptor M2 抗体 (AA 185-234)
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Quick Overview for Muscarinic Acetylcholine Receptor M2 抗体 (AA 185-234) (ABIN1535645)
抗原
See all Muscarinic Acetylcholine Receptor M2 (CHRM2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 185-234
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原理
- mAChR M2 Antibody
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特异性
- MAChR M2 Polyclonal Antibody detects endogenous levels of mAChR M2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human CHRM2. AA range:185-234
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))
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别名
- CHRM2
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背景
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Synonyms: CHRM2, Muscarinic acetylcholine receptor M2
Background: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008],
Gene Name: CHRM2
Protein Name: Muscarinic acetylcholine receptor M2
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分子量
- 51 kDa
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基因ID
- 1129
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OMIM
- 118493
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UniProt
- P08172
抗原
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