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Muscarinic Acetylcholine Receptor M2 抗体 (AA 185-234)

The 兔 多克隆 anti-Muscarinic Acetylcholine Receptor M2 antibody (ABIN1535645) specifically detects Muscarinic Acetylcholine Receptor M2 in WB, ELISA 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1535645
发货至: 中国
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Quick Overview for Muscarinic Acetylcholine Receptor M2 抗体 (AA 185-234) (ABIN1535645)

抗原

See all Muscarinic Acetylcholine Receptor M2 (CHRM2) 抗体
Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))

适用

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  • 4
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人, 小鼠, 大鼠

宿主

  • 94
  • 14
  • 2
  • 2
  • 1
兔

克隆类型

  • 80
  • 33
多克隆

标记

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  • 1
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This Muscarinic Acetylcholine Receptor M2 antibody is un-conjugated

应用范围

  • 91
  • 38
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Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    • 2
    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    AA 185-234

    原理

    mAChR M2 Antibody

    特异性

    MAChR M2 Polyclonal Antibody detects endogenous levels of mAChR M2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human CHRM2. AA range:185-234

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))

    别名

    CHRM2

    背景

    Synonyms: CHRM2, Muscarinic acetylcholine receptor M2

    Background: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008],

    Gene Name: CHRM2

    Protein Name: Muscarinic acetylcholine receptor M2

    分子量

    51 kDa

    基因ID

    1129

    OMIM

    118493

    UniProt

    P08172
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