Serotonin Receptor 2B 抗体 (AA 15-64)
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Quick Overview for Serotonin Receptor 2B 抗体 (AA 15-64) (ABIN1535553)
抗原
See all Serotonin Receptor 2B (HTR2B) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 15-64
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原理
- SR-2B Antibody
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特异性
- SR-2B Polyclonal Antibody detects endogenous levels of SR-2B protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human HTR2B. AA range:15-64
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Serotonin Receptor 2B (HTR2B) (5-Hydroxytryptamine (serotonin) Receptor 2B (HTR2B))
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别名
- HTR2B
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背景
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Synonyms: HTR2B, 5-hydroxytryptamine receptor 2B, 5-HT-2B, 5-HT2B, Serotonin receptor 2B
Background: This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016],
Gene Name: HTR2B
Protein Name: 5-hydroxytryptamine receptor 2B
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分子量
- 54 kDa
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基因ID
- 3357
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OMIM
- 601122
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UniProt
- P41595
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途径
- JAK/STAT Signaling, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process
抗原
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