PLAGL1 抗体 (AA 311-360)
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北京 101111
Quick Overview for PLAGL1 抗体 (AA 311-360) (ABIN1535506)
抗原
See all PLAGL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 311-360
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原理
- ZAC1 Antibody
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特异性
- ZAC1 Polyclonal Antibody detects endogenous levels of ZAC1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human PLAGL1. AA range:311-360
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))
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别名
- PLAGL1
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背景
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Synonyms: PLAGL1, LOT1, ZAC, Zinc finger protein PLAGL1, Lost on transformation 1, LOT-1, Pleiomorphic adenoma-like protein 1, Tumor supressor ZAC
Background: This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM). Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues. [provided by RefSeq, Nov 2015],
Gene Name: PLAGL1
Protein Name: Zinc finger protein PLAGL1
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分子量
- 50 kDa
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基因ID
- 5325
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OMIM
- 603044
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UniProt
- Q9UM63
抗原
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