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ZP4 抗体 (AA 231-280)

The 兔 多克隆 anti-ZP4 antibody is suitable to detect ZP4 in samples from 人, 大鼠 和 小鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN1535494
发货至: 中国
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Quick Overview for ZP4 抗体 (AA 231-280) (ABIN1535494)

抗原

See all ZP4 抗体
ZP4 (Zona Pellucida Glycoprotein 4 (ZP4))

适用

  • 28
  • 3
  • 2
  • 1
人, 大鼠, 小鼠

宿主

  • 28
兔

克隆类型

  • 28
多克隆

标记

  • 14
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ZP4 antibody is un-conjugated

应用范围

  • 18
  • 13
  • 10
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 231-280

    原理

    ZP4 Antibody

    特异性

    ZP4 Polyclonal Antibody detects endogenous levels of ZP4 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human ZP4. AA range:231-280

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    ZP4 (Zona Pellucida Glycoprotein 4 (ZP4))

    别名

    ZP4

    背景

    Synonyms: ZP4, ZPB, Zona pellucida sperm-binding protein 4, Zona pellucida glycoprotein 4, Zp-4, Zona pellucida protein B

    Background: The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been

    Gene Name: ZP4

    Protein Name: Zona pellucida sperm-binding protein 4

    分子量

    59 kDa

    基因ID

    57829

    UniProt

    Q12836
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