ZP4 抗体 (AA 231-280)
Our Local Distributor
北京 101111
Quick Overview for ZP4 抗体 (AA 231-280) (ABIN1535494)
抗原
See all ZP4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 231-280
-
原理
- ZP4 Antibody
-
特异性
- ZP4 Polyclonal Antibody detects endogenous levels of ZP4 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human ZP4. AA range:231-280
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- ZP4 (Zona Pellucida Glycoprotein 4 (ZP4))
-
别名
- ZP4
-
背景
-
Synonyms: ZP4, ZPB, Zona pellucida sperm-binding protein 4, Zona pellucida glycoprotein 4, Zp-4, Zona pellucida protein B
Background: The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been
Gene Name: ZP4
Protein Name: Zona pellucida sperm-binding protein 4
-
分子量
- 59 kDa
-
基因ID
- 57829
-
UniProt
- Q12836
抗原
-