UGDH 抗体 (AA 391-440)
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北京 101111
Quick Overview for UGDH 抗体 (AA 391-440) (ABIN1535450)
抗原
See all UGDH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 391-440
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原理
- UDP-GlcDH Antibody
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特异性
- UDP-GlcDH Polyclonal Antibody detects endogenous levels of UDP-GlcDH protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human UGDH. AA range:391-440
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))
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别名
- UGDH
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背景
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Synonyms: UGDH, UDP-glucose 6-dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH
Background: The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
Gene Name: UGDH
Protein Name: UDP-glucose 6-dehydrogenase
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分子量
- 55 kDa
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基因ID
- 7358
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OMIM
- 603370
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UniProt
- O60701
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途径
- Glycosaminoglycan Metabolic Process
抗原
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