UBAC1 抗体 (AA 91-140)
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北京 101111
Quick Overview for UBAC1 抗体 (AA 91-140) (ABIN1535446)
抗原
See all UBAC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 91-140
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原理
- GBDR1 Antibody
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特异性
- GBDR1 Polyclonal Antibody detects endogenous levels of GBDR1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human UBAC1. AA range:91-140
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- UBAC1 (UBA Domain Containing 1 (UBAC1))
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别名
- UBAC1
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背景
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Synonyms: UBAC1, GBDR1, KPC2, UBADC1, Ubiquitin-associated domain-containing protein 1, UBA domain-containing protein 1, E3 ubiquitin-protein ligase subunit KPC2, Glialblastoma cell differentiation-related protein 1, Kip1 ubiquitination-promoting com
Background: function:Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.,pathway:Protein modification, protein ubiquitination.,similarity:Contains 1 STI1 domain.,similarity:Contains 1 ubiquitin-like domain.,similarity:Contains 2 UBA domains.,subunit:Component of the KPC complex composed of RNF123/KPC1 and UBAC1/KPC2. Interacts with RNF123 via its N-terminal domain. Interacts with the proteasome via its N-terminal domain.,tissue specificity:Ubiquitous.,
Gene Name: UBAC1
Protein Name: Ubiquitin-associated domain-containing protein 1
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分子量
- 45 kDa
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基因ID
- 10422
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OMIM
- 608129
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UniProt
- Q9BSL1
抗原
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