RGS7 抗体 (AA 155-204)
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北京 101111
Quick Overview for RGS7 抗体 (AA 155-204) (ABIN1535286)
抗原
See all RGS7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 155-204
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原理
- RGS7 Antibody
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特异性
- RGS7 Polyclonal Antibody detects endogenous levels of RGS7 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human RGS7. AA range:155-204
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- RGS7 (Regulator of G-Protein Signaling 7 (RGS7))
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别名
- RGS7
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背景
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Synonyms: RGS7, Regulator of G-protein signaling 7, RGS7
Background: function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(o)-alpha is specifically enhanced by the RGS6/GNG5 dimer. May play a role in synaptic vesicle exocytosis. May play important role in the rapid regulation of neuronal excitability and the cellular responses to short-lived stimulations.,PTM:Palmitoylated.,PTM:Phosphorylation and subsequent interaction with 14-3-3 proteins inhibits GAP activity.,similarity:Contains 1 DEP domain.,similarity:Contains 1 G protein gamma domain.,similarity:Contains 1 RGS domain.,subunit:Heterodimer with GNG5. Interacts with RGS7BP, leading to regulate the subcellular location of the heterodimer formed with Gbeta5 (By similarity). Interacts with 14-3-3 protein Tau and SNAP25BP.,
Gene Name: RGS7
Protein Name: Regulator of G-protein signaling 7
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分子量
- 57 kDa
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基因ID
- 6000
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OMIM
- 602517
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UniProt
- P49802
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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