RRAGA/B 抗体 (AA 264-313)
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北京 101111
Quick Overview for RRAGA/B 抗体 (AA 264-313) (ABIN1535267)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 264-313
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原理
- Rag A/B Antibody
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特异性
- Rag A/B Polyclonal Antibody detects endogenous levels of Rag A/B protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human RRAGA/B. AA range:264-313
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亚型
- IgG
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anti-Ras-Related GTP Binding A/B (RRAGA/B) (C-Term) antibody
RRAGA/B 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ras-Related GTP Binding A/B (RRAGA/B) (C-Term) antibodyRRAGA/B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras-Related GTP Binding A/B (RRAGA/B) (C-Term) antibodyRRAGA/B 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- RRAGA/B (Ras-Related GTP Binding A/B (RRAGA/B))
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别名
- RRAGA/B
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背景
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Synonyms: RRAGA, Ras-related GTP-binding protein A, Rag A, RagA, Adenovirus E3 14.7 kDa-interacting protein 1, FIP-1, RRAGB, Ras-related GTP-binding protein B, Rag B, RagB
Background: function:Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.,similarity:Belongs to the GTR/RAG GTP-binding protein family.,subcellular location:Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state. Colocalizes in vivo with adenovirus E3-14.7K mainly to the cytoplasm especially near the nuclear membrane and in discrete foci on or near the plasma membrane.,subunit:Can occur as a homodimer, or form a heterodimer with RRAGC or RRAGD in a sequence-independent manner. Binds GTP. The GTP-bound form of RRAGA interacts with NOL8. Interacts with adenovirus E3 14.7 kDa protein.,tissue specificity:Ubiquitously expressed with highest levels of expression in skeletal muscle, heart, and brain.,
Gene Name: RRAGA/RRAGB
Protein Name: Ras-related GTP-binding protein A/B
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分子量
- 36 kDa
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基因ID
- 10670, 10325
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UniProt
- Q7L523
抗原
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