RAB11FIP2 抗体 (AA 340-389)
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Quick Overview for RAB11FIP2 抗体 (AA 340-389) (ABIN1535246)
抗原
See all RAB11FIP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 340-389
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原理
- Rab11-FIP2 Antibody
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特异性
- Rab11-FIP2 Polyclonal Antibody detects endogenous levels of Rab11-FIP2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human RAB11FIP2. AA range:340-389
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- RAB11FIP2 (RAB11 Family Interacting Protein 2 (Class I) (RAB11FIP2))
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别名
- RAB11FIP2
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背景
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Synonyms: RAB11FIP2, KIAA0941, Rab11 family-interacting protein 2, Rab11-FIP2, NRip11
Background: function:A Rab11 effector protein acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Binds preferentially to phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA).,similarity:Contains 1 C2 domain.,subcellular location:Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane.,subunit:Homooligomerizes in a Rab11-independent manner. Forms an heterooligomeric complex with RAB11FIP4. Interacts with AP2A1, MYO5B, RAB11A, RAB11B, RAB25 and REPS1. Interacts with RAB11A/RAB11B that has been activated by GTP binding.,
Gene Name: RAB11FIP2
Protein Name: Rab11 family-interacting protein 2
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分子量
- 58 kDa
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基因ID
- 22841
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OMIM
- 608599
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UniProt
- Q7L804
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途径
- Hormone Transport, Carbohydrate Homeostasis
抗原
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