RCC2 抗体 (AA 473-522)
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Quick Overview for RCC2 抗体 (AA 473-522) (ABIN1535228)
抗原
See all RCC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 473-522
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原理
- RCC2 Antibody
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特异性
- RCC2 Polyclonal Antibody detects endogenous levels of RCC2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human RCC2. AA range:473-522
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- RCC2 (Regulator of Chromosome Condensation 2 (RCC2))
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别名
- RCC2
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背景
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Synonyms: RCC2, KIAA1470, TD60, Protein RCC2, RCC1-like protein TD-60, Telophase disk protein of 60 kDa
Background: function:Required for completion of mitosis and cytokinesis. May function as a guanine nucleotide exchange factor for the small GTPase RAC1.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 7 RCC1 repeats.,subcellular location:Appears in the nucleus at G2, then concentrates at the inner centromere region of chromosomes during prophase. Redistributes to the midzone of the mitotic spindle during anaphase. Here, the protein covers the entire equatorial diameter from cortex to cortex.,subunit:Binds preferentially to the nucleotide-free form of RAC1. Interacts with microtubules.,
Gene Name: RCC2
Protein Name: Protein RCC2
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分子量
- 56 kDa
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基因ID
- 55920
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OMIM
- 609587
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UniProt
- Q9P258
抗原
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