Prosaposin 抗体 (AA 307-356)
Our Local Distributor
北京 101111
Quick Overview for Prosaposin 抗体 (AA 307-356) (ABIN1535203)
抗原
See all Prosaposin (PSAP) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 307-356
-
原理
- Saposin Antibody
-
特异性
- Saposin Polyclonal Antibody detects endogenous levels of Saposin protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human PSAP. AA range:307-356
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- Prosaposin (PSAP)
-
别名
- PSAP
-
背景
-
Synonyms: PSAP, GLBA, SAP1, Proactivator polypeptide
Background: This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016],
Gene Name: PSAP
Protein Name: Proactivator polypeptide
-
分子量
- 58 kDa
-
基因ID
- 5660
-
OMIM
- 176801
-
UniProt
- P07602
-
途径
- Positive Regulation of Endopeptidase Activity
抗原
-