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Prosaposin 抗体 (AA 307-356)

The 兔 多克隆 anti-Prosaposin antibody is suitable to detect Prosaposin in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, ELISA 和 IF.
产品编号 ABIN1535203
发货至: 中国
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Quick Overview for Prosaposin 抗体 (AA 307-356) (ABIN1535203)

抗原

See all Prosaposin (PSAP) 抗体
Prosaposin (PSAP)

适用

人, 小鼠, 大鼠

宿主

  • 72
  • 18
兔

克隆类型

  • 61
  • 29
多克隆

标记

  • 44
  • 5
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Prosaposin antibody is un-conjugated

应用范围

  • 67
  • 43
  • 27
  • 20
  • 18
  • 17
  • 16
  • 14
  • 14
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 13
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 307-356

    原理

    Saposin Antibody

    特异性

    Saposin Polyclonal Antibody detects endogenous levels of Saposin protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human PSAP. AA range:307-356

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Prosaposin (PSAP)

    别名

    PSAP

    背景

    Synonyms: PSAP, GLBA, SAP1, Proactivator polypeptide

    Background: This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016],

    Gene Name: PSAP

    Protein Name: Proactivator polypeptide

    分子量

    58 kDa

    基因ID

    5660

    OMIM

    176801

    UniProt

    P07602

    途径

    Positive Regulation of Endopeptidase Activity
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