PVRL4 抗体 (AA 312-361)
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北京 101111
Quick Overview for PVRL4 抗体 (AA 312-361) (ABIN1535179)
抗原
See all PVRL4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 312-361
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原理
- Nectin 4 Antibody
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特异性
- Nectin 4 Polyclonal Antibody detects endogenous levels of Nectin 4 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human PVRL4. AA range:312-361
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))
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别名
- PVRL4
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背景
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Synonyms: PVRL4, LNIR, PRR4, Poliovirus receptor-related protein 4, Ig superfamily receptor LNIR, Nectin-4
Background: This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011],
Gene Name: PVRL4
Protein Name: Poliovirus receptor-related protein 4
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分子量
- 55 kDa
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基因ID
- 81607
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OMIM
- 609607
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UniProt
- Q96NY8
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途径
- Cell-Cell Junction Organization
抗原
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