PEX7 抗体 (AA 204-253)
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北京 101111
Quick Overview for PEX7 抗体 (AA 204-253) (ABIN1535157)
抗原
See all PEX7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 204-253
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原理
- Peroxin 7 Antibody
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特异性
- Peroxin 7 Polyclonal Antibody detects endogenous levels of Peroxin 7 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human PEX7. AA range:204-253
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PEX7 (Peroxisomal Biogenesis Factor 7 (PEX7))
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别名
- PEX7
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背景
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Synonyms: PEX7, PTS2R, Peroxisomal targeting signal 2 receptor, PTS2 receptor, Peroxin-7
Background: This gene encodes the cytosolic receptor for the set of peroxisomal matrix enzymes targeted to the organelle by the peroxisome targeting signal 2 (PTS2). Defects in this gene cause peroxisome biogenesis disorders (PBDs), which are characterized by multiple defects in peroxisome function. There are at least 14 complementation groups for PBDs, with more than one phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene have been associated with PBD complementation group 11 (PBD-CG11) disorders, rhizomelic chondrodysplasia punctata type 1 (RCDP1), and Refsum disease (RD). [provided by RefSeq, Oct 2008],
Gene Name: PEX7
Protein Name: Peroxisomal targeting signal 2 receptor
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分子量
- 35 kDa
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基因ID
- 5191
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OMIM
- 601757
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UniProt
- O00628
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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