NXF3 抗体 (AA 72-121)
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北京 101111
Quick Overview for NXF3 抗体 (AA 72-121) (ABIN1535124)
抗原
See all NXF3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 72-121
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原理
- NXF3 Antibody
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特异性
- NXF3 Polyclonal Antibody detects endogenous levels of NXF3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human NXF3. AA range:72-121
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- NXF3 (Nuclear RNA Export Factor 3 (NXF3))
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别名
- NXF3
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背景
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Synonyms: NXF3, TAPL3, Nuclear RNA export factor 3, TAP-like protein 3, TAPL-3
Background: This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. [provided by RefSeq, Jul 2008],
Gene Name: NXF3
Protein Name: Nuclear RNA export factor 3
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分子量
- 60 kDa
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基因ID
- 56000
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OMIM
- 300316
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UniProt
- Q9H4D5
抗原
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