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Nicalin 抗体 (AA 474-523)

The 兔 多克隆 anti-Nicalin antibody is suitable to detect Nicalin in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN1535110
发货至: 中国
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Quick Overview for Nicalin 抗体 (AA 474-523) (ABIN1535110)

抗原

See all Nicalin (NCLN) 抗体
Nicalin (NCLN)

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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多克隆

标记

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This Nicalin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 474-523

    原理

    Nicalin Antibody

    特异性

    Nicalin Polyclonal Antibody detects endogenous levels of Nicalin protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human NCLN. AA range:474-523

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Nicalin (NCLN)

    别名

    NCLN

    背景

    Synonyms: NCLN, Nicalin, Nicastrin-like protein

    Background: function:May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.,similarity:Belongs to the nicastrin family.,subunit:Interacts with NOMO2. Due to the strong similarity between NOMO1, NOMO2 and NOMO3, it probably also interacts with NOMO1 and NOMO3. Participates in a large protein complex, which is not related to the gamma-secretase complex.,tissue specificity:Highly expressed in pancreas and skeletal muscle and, at lower levels, in heart.,

    Gene Name: NCLN

    Protein Name: Nicalin

    分子量

    62 kDa

    基因ID

    56926

    OMIM

    609156

    UniProt

    Q969V3
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