CHRNA10 抗体 (AA 394-443)
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北京 101111
Quick Overview for CHRNA10 抗体 (AA 394-443) (ABIN1535099)
抗原
See all CHRNA10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 394-443
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原理
- AChRα10 Antibody
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特异性
- AChRα10 Polyclonal Antibody detects endogenous levels of AChRα10 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human CHRNA10. AA range:394-443
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亚型
- IgG
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anti-Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10) (AA 25-237) antibody
CHRNA10 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6C10E8 unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10) (AA 25-237) antibodyCHRNA10 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4E2D1 unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10) (AA 25-240) antibodyCHRNA10 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10) antibodyCHRNA10 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10) (C-Term) antibodyCHRNA10 适用: 人, 大鼠, 小鼠 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10) (AA 179-206) antibodyCHRNA10 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32240 unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10) (C-Term) antibodyCHRNA10 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10) (AA 25-240) antibodyCHRNA10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10) (C-Term) antibodyCHRNA10 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10) (2nd Cytoplasmic Loop), (AA 411-425) antibodyCHRNA10 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))
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别名
- CHRNA10
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背景
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Synonyms: CHRNA10, NACHRA10, Neuronal acetylcholine receptor subunit alpha-10, Nicotinic acetylcholine receptor subunit alpha-10, NACHR alpha-10
Background: function:Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.,miscellaneous:The hetero-oligomeric receptor composed of CHRNA9 and CHRNA10 has an atypical pharmacological profile, binding several non-nicotinic ligands including strychnine (a glycine receptor antagonist) and atropine (a muscarinic acetylcholine receptor antagonist).,similarity:Belongs to the ligand-gated ionic channel (TC 1.A.9) family.,subunit:Forms hetero-oligomeric channels in conjunction with CHRNA9. The native outer hair cell receptor may be composed of CHRNA9-CHRNA10 hetero-oligomers.,tissue specificity:Expressed in inner-ear tissue, tonsil, immortalized B-cells, cultured T-cells and peripheral blood lymphocytes.,
Gene Name: CHRNA10
Protein Name: Neuronal acetylcholine receptor subunit alpha-10
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分子量
- 49 kDa
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基因ID
- 57053
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OMIM
- 606372
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UniProt
- Q9GZZ6
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途径
- Sensory Perception of Sound, Synaptic Membrane
抗原
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