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Neurexin 1 抗体 (AA 502-551)

This 兔 多克隆 antibody specifically detects Neurexin 1 in WB 和 IHC. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN1535088
发货至: 中国
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Quick Overview for Neurexin 1 抗体 (AA 502-551) (ABIN1535088)

抗原

See all Neurexin 1 (NRXN1) 抗体
Neurexin 1 (NRXN1)

适用

人, 大鼠, 小鼠

宿主

  • 33
  • 9
  • 1
  • 1
兔

克隆类型

  • 36
  • 8
多克隆

标记

  • 25
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Neurexin 1 antibody is un-conjugated

应用范围

  • 32
  • 25
  • 11
  • 8
  • 7
  • 5
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 12
    • 11
    • 9
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 502-551

    原理

    Neurexin I Antibody

    特异性

    Neurexin I Polyclonal Antibody detects endogenous levels of Neurexin I protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human NRXN1. AA range:502-551

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,IHC 1:50-300

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Neurexin 1 (NRXN1)

    别名

    NRXN1

    背景

    Synonyms: NRXN1, KIAA0578, Neurexin-1-alpha, Neurexin I-alpha

    Background: NRXN1 (neurexin 1) encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for NRXN1 in the 3' region. Mutations in NRXN1 are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia.

    Gene Name: NRXN1

    Protein Name: Neurexin-1-alpha

    分子量

    161 kDa

    基因ID

    9378

    OMIM

    600565

    UniProt

    Q9ULB1

    途径

    Synaptic Membrane, Skeletal Muscle Fiber Development
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