Nesprin3 抗体 (AA 169-218)
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Quick Overview for Nesprin3 抗体 (AA 169-218) (ABIN1535082)
抗原
See all Nesprin3 (C14orf49) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 169-218
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原理
- Nesprin-3 Antibody
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特异性
- Nesprin-3 Polyclonal Antibody detects endogenous levels of Nesprin-3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human C14orf49. AA range:169-218
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))
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别名
- C14orf49
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背景
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Synonyms: SYNE3, C14orf49, Nesprin-3, Nuclear envelope spectrin repeat protein 3
Background: function:Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which theters the nucleus to the cytoskeleton by binding PLEC1/Plectin which can associate with the intermediate filament system.,similarity:Belongs to the nesprin family.,similarity:Contains 1 KASH domain.,similarity:Contains 2 spectrin repeats.,subcellular location:Located at the rough reticulum endoplasmic (RER) in some cells.,subunit:Interacts with actin-binding domain of PLEC1/plectin.,
Gene Name: SYNE3
Protein Name: Nesprin-3
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分子量
- 112 kDa
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基因ID
- 161176
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OMIM
- 610861
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UniProt
- Q6ZMZ3
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途径
- Maintenance of Protein Location
抗原
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