MT-ND1 抗体 (AA 176-225)
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北京 101111
Quick Overview for MT-ND1 抗体 (AA 176-225) (ABIN485690)
抗原
See all MT-ND1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 176-225
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原理
- ND1 Antibody
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特异性
- ND1 Polyclonal Antibody detects endogenous levels of ND1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MT-ND1. AA range:176-225
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亚型
- IgG
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anti-Mitochondrially Encoded NADH Dehydrogenase 1 (MT-ND1) antibody
MT-ND1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrially Encoded NADH Dehydrogenase 1 (MT-ND1) antibodyMT-ND1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrially Encoded NADH Dehydrogenase 1 (MT-ND1) (AA 1-100) antibodyMT-ND1 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrially Encoded NADH Dehydrogenase 1 (MT-ND1) (Internal Region) antibodyMT-ND1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrially Encoded NADH Dehydrogenase 1 (MT-ND1) (AA 186-270) antibodyMT-ND1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrially Encoded NADH Dehydrogenase 1 (MT-ND1) (AA 23-67) antibodyMT-ND1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrially Encoded NADH Dehydrogenase 1 (MT-ND1) (AA 21-71) antibodyMT-ND1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mitochondrially Encoded NADH Dehydrogenase 1 (MT-ND1) (AA 21-71) antibodyMT-ND1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3H3 unconjugated
anti-Mitochondrially Encoded NADH Dehydrogenase 1 (MT-ND1) (AA 34-68), (N-Term) antibodyMT-ND1 适用: 人 WB 宿主: 兔 Polyclonal RB50705 unconjugated
anti-Mitochondrially Encoded NADH Dehydrogenase 1 (MT-ND1) antibodyMT-ND1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MT-ND1 (Mitochondrially Encoded NADH Dehydrogenase 1 (MT-ND1))
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别名
- MT-ND1
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背景
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Synonyms: MT-ND1, MTND1, NADH1, ND1, NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1
Background: catalytic activity:NADH + ubiquinone = NAD(+) + ubiquinol.,disease:Defects in MT-ND1 are a cause of Leber hereditary optic neuropathy (LHON) [MIM:535000]. LHON is a maternally inherited disease resulting in acute or subacute loss of central vision, due to optic nerve dysfunction. Cardiac conduction defects and neurological defects have also been described in some patients. LHON results from primary mitochondrial DNA mutations affecting the respiratory chain complexes.,disease:Defects in MT-ND1 are a cause of mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes syndrome (MELAS) [MIM:540000]. MELAS is a genetically heterogenious disorder, characterized by episodic vomiting, seizures, and recurrent cerebral insults resembling strokes and causing hemiparesis, hemianopsia, or cortical blindness.,disease:Defects in MT-ND1 may be associated with mitochondrial susceptibility to Alzheimer disease (AD) [MIM:502500].,disease:Defects in MT-ND1 may be associated with non-insulin-dependent diabetes mellitus (NIDDM).,function:Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I subunit 1 family.,
Gene Name: MT-ND1
Protein Name: NADH-ubiquinone oxidoreductase chain 1
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分子量
- 35 kDa
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基因ID
- 4535
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OMIM
- 502500
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UniProt
- P03886
抗原
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