Myomesin 1 抗体 (AA 824-873)
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Quick Overview for Myomesin 1 抗体 (AA 824-873) (ABIN1535047)
抗原
See all Myomesin 1 (MYOM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 824-873
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原理
- Myomesin-1 Antibody
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特异性
- Myomesin-1 Polyclonal Antibody detects endogenous levels of Myomesin-1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MYOM1. AA range:824-873
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Myomesin 1 (MYOM1)
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别名
- MYOM1
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背景
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Synonyms: MYOM1, Myomesin-1, 190 kDa connectin-associated protein, 190 kDa titin-associated protein, Myomesin family member 1
Background: The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II, in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50 % sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure
Gene Name: MYOM1
Protein Name: Myomesin-1
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分子量
- 162 kDa
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基因ID
- 8736
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OMIM
- 603508
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UniProt
- P52179
抗原
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