MNDA 抗体 (AA 358-407)
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北京 101111
Quick Overview for MNDA 抗体 (AA 358-407) (ABIN485664)
抗原
See all MNDA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 358-407
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原理
- MNDA Antibody
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特异性
- MNDA Polyclonal Antibody detects endogenous levels of MNDA protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MNDA. AA range:358-407
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))
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别名
- MNDA
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背景
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Synonyms: MNDA, Myeloid cell nuclear differentiation antigen
Background: The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. [provided by RefSeq, Jul 2008],
Gene Name: MNDA
Protein Name: Myeloid cell nuclear differentiation antigen
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分子量
- 45 kDa
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基因ID
- 4332
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OMIM
- 159553
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UniProt
- P41218
抗原
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