MBTPS2 抗体 (AA 301-350)
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北京 101111
Quick Overview for MBTPS2 抗体 (AA 301-350) (ABIN1535018)
抗原
See all MBTPS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-350
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原理
- S2P Antibody
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特异性
- S2P Polyclonal Antibody detects endogenous levels of S2P protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MBTPS2. AA range:301-350
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亚型
- IgG
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anti-Membrane-Bound Transcription Factor Peptidase, Site 2 (MBTPS2) (AA 312-418) antibody
MBTPS2 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 1A3 unconjugated
anti-Membrane-Bound Transcription Factor Peptidase, Site 2 (MBTPS2) (AA 15-44), (N-Term) antibodyMBTPS2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32439 unconjugated
anti-Membrane-Bound Transcription Factor Peptidase, Site 2 (MBTPS2) antibodyMBTPS2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-2000 IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MBTPS2 (Membrane-Bound Transcription Factor Peptidase, Site 2 (MBTPS2))
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别名
- MBTPS2
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背景
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Synonyms: MBTPS2, S2P, Membrane-bound transcription factor site-2 protease, Endopeptidase S2P, Sterol regulatory element-binding proteins intramembrane protease, SREBPs intramembrane protease
Background: This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome), IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.[provided by RefSeq, Aug 2009],
Gene Name: MBTPS2
Protein Name: Membrane-bound transcription factor site-2 protease
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分子量
- 57 kDa
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基因ID
- 51360
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OMIM
- 300294
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UniProt
- O43462
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途径
- ER-Nucleus Signaling
抗原
-
