LRRC41 抗体 (AA 391-440)
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北京 101111
Quick Overview for LRRC41 抗体 (AA 391-440) (ABIN1535000)
抗原
See all LRRC41 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 391-440
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原理
- LRRC41 Antibody
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特异性
- LRRC41 Polyclonal Antibody detects endogenous levels of LRRC41 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human LRRC41. AA range:391-440
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- LRRC41 (Leucine Rich Repeat Containing 41 (LRRC41))
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别名
- LRRC41
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背景
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Synonyms: LRRC41, MUF1, PP7759, Leucine-rich repeat-containing protein 41, Protein Muf1
Background: caution:It is uncertain whether Met-1 or Met-23 is the initiator.,domain:The elongin BC complex binding domain is also known as BC-box with the consensus [APST]-L-x(3)-C-x(3)-[AILV].,function:Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification, protein ubiquitination.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Translation N-terminally extended.,similarity:Contains 7 LRR (leucine-rich) repeats.,subunit:Part of an E3 ubiquitin-protein ligase complex with Elongin BC (TCEB1 and TCEB2), RBX1 and CUL5. Component of a probable ECS(LRRC41) complex which contains CUL5, RNF7/RBX2, Elongin BC and LRRC41. Interacts with CUL5, RNF7, TCEB1 and TCEB2.,
Gene Name: LRRC41
Protein Name: Leucine-rich repeat-containing protein 41
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分子量
- 88 kDa
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基因ID
- 10489
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UniProt
- Q15345
抗原
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