GUF1 抗体 (AA 421-470)
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北京 101111
Quick Overview for GUF1 抗体 (AA 421-470) (ABIN1534964)
抗原
See all GUF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 421-470
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原理
- GUF1 Antibody
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特异性
- GUF1 Polyclonal Antibody detects endogenous levels of GUF1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human GUF1. AA range:421-470
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- GUF1 (GUF1 GTPase Homolog (GUF1))
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别名
- GUF1
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背景
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Synonyms: GUF1, Translation factor GUF1, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1, Ribosomal back-translocase
Background: This gene encodes a GTPase that triggers back-translocation of the elongating ribosome during mitochondrial protein synthesis. The protein contains a highly conserved C-terminal domain not found in other GTPases that facilitates tRNA binding. The encoded protein is thought to prevent misincorporation of amino acids in stressful, suboptimal conditions. An allelic variant in this gene has been associated with early infantile epileptic encephalopathy-40. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016],
Gene Name: GUF1
Protein Name: Translation factor GUF1 mitochondrial
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分子量
- 74 kDa
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基因ID
- 60558
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UniProt
- Q8N442
抗原
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