GDF15 抗体 (AA 31-80)
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北京 101111
Quick Overview for GDF15 抗体 (AA 31-80) (ABIN1534953)
抗原
See all GDF15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-80
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原理
- GDF-15 Antibody
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特异性
- GDF-15 Polyclonal Antibody detects endogenous levels of GDF-15 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human GDF15. AA range:31-80
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- GDF15 (Growth Differentiation Factor 15 (GDF15))
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别名
- GDF15
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背景
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Synonyms: GDF15, MIC1, PDF, PLAB, PTGFB, Growth/differentiation factor 15, GDF-15, Macrophage inhibitory cytokine 1, MIC-1, NSAID-activated gene 1 protein, NAG-1, NSAID-regulated gene 1 protein, NRG-1, Placental TGF-beta, Placental bone morphogenetic
Background: growth differentiation factor 15(GDF15) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress. [provided by RefSeq, Aug 2016],
Gene Name: GDF15
Protein Name: Growth/differentiation factor 15
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分子量
- 34 kDa
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基因ID
- 9518
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OMIM
- 605312
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UniProt
- Q99988
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途径
- SARS-CoV-2 Protein Interactome
抗原
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