ZNRF2 抗体 (AA 161-210)
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北京 101111
Quick Overview for ZNRF2 抗体 (AA 161-210) (ABIN1534873)
抗原
See all ZNRF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 161-210
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原理
- ZNRF2 Antibody
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特异性
- ZNRF2 Polyclonal Antibody detects endogenous levels of ZNRF2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human ZNRF2. AA range:161-210
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亚型
- IgG
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anti-Zinc and Ring Finger 2 (ZNRF2) (C-Term) antibody
ZNRF2 适用: 人, 小鼠, 大鼠, 斑马鱼 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc and Ring Finger 2 (ZNRF2) (AA 2-36), (N-Term) antibodyZNRF2 适用: 人 WB 宿主: 兔 Polyclonal RB49907 unconjugated
anti-Zinc and Ring Finger 2 (ZNRF2) (AA 146-207) antibodyZNRF2 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ZNRF2 (Zinc and Ring Finger 2 (ZNRF2))
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别名
- ZNRF2
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背景
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Synonyms: ZNRF2, RNF202, E3 ubiquitin-protein ligase ZNRF2, Protein Ells2, RING finger protein 202, Zinc/RING finger protein 2
Background: domain:The RING-type zinc finger domain is required for E3 ligase activity.,function:May play a role in the establisment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.,pathway:Protein modification, protein ubiquitination.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 RING-type zinc finger.,subcellular location:Present in presynaptic plasma membranes in neurons.,subunit:Interacts with UBE2N.,tissue specificity:Highly expressed in the brain, with higher expression during development than in adult. Expressed also in mammary glands, testis, colon and kidney.,
Gene Name: ZNRF2
Protein Name: E3 ubiquitin-protein ligase ZNRF2
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分子量
- 24 kDa
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基因ID
- 223082
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OMIM
- 612061
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UniProt
- Q8NHG8
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途径
- Synaptic Membrane
抗原
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