CD3EAP 抗体 (AA 441-490)
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Quick Overview for CD3EAP 抗体 (AA 441-490) (ABIN1534844)
抗原
See all CD3EAP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 441-490
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原理
- CD3EAP Antibody
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特异性
- CD3EAP Polyclonal Antibody detects endogenous levels of CD3EAP protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human CD3EAP. AA range:441-490
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亚型
- IgG
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anti-CD3e Molecule, epsilon Associated Protein (CD3EAP) (AA 404-454) antibody
CD3EAP 适用: 人 IHC, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-CD3e Molecule, epsilon Associated Protein (CD3EAP) (AA 2-110) antibodyCD3EAP 适用: 人 ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 6A6 unconjugated
anti-CD3e Molecule, epsilon Associated Protein (CD3EAP) (AA 289-404) antibodyCD3EAP 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD3e Molecule, epsilon Associated Protein (CD3EAP) (AA 54-81), (N-Term) antibodyCD3EAP 适用: 人 WB 宿主: 兔 Polyclonal RB41983 unconjugated
anti-CD3e Molecule, epsilon Associated Protein (CD3EAP) (Center) antibodyCD3EAP 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD3e Molecule, epsilon Associated Protein (CD3EAP) (AA 2-110) antibodyCD3EAP 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-CD3e Molecule, epsilon Associated Protein (CD3EAP) (C-Term) antibodyCD3EAP 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD3e Molecule, epsilon Associated Protein (CD3EAP) (C-Term) antibodyCD3EAP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD3e Molecule, epsilon Associated Protein (CD3EAP) (AA 404-454) antibodyCD3EAP 适用: 人 WB, IP, IF/ICC, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-CD3e Molecule, epsilon Associated Protein (CD3EAP) (AA 225-275) antibodyCD3EAP 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CD3EAP (CD3e Molecule, epsilon Associated Protein (CD3EAP))
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别名
- CD3EAP
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背景
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Synonyms: CD3EAP, ASE1, CAST, PAF49, DNA-directed RNA polymerase I subunit RPA34, A34.5, Antisense to ERCC-1 protein, ASE-1, CD3-epsilon-associated protein, CAST, CD3E-associated protein, RNA polymerase I-associated factor PAF49
Background: caution:It is not known whether the so-called human ASE1 and human CAST proteins represent two sides of a single gene product with sharply different functional characteristics. Experiments done with the mouse homolog protein are in favor of an implication of this gene in rRNA transcription instead of T-cell receptor signaling.,function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Isoform 1 is involved in UBTF-activated transcription, presumably at a step following PIC formation.,function:Isoform 2 has been described as a component of preformed T-cell receptor (TCR) complex.,miscellaneous:It is in an antisense orientation to and overlaps the gene of the DNA repair enzyme ERCC1. This gene overlap is conserved in mouse suggesting an important biologic function.,PTM:Isoform 1 is phosphorylated on tyrosine residues in initiation-competent Pol I-beta complexes but not in Pol I-alpha complexes.,PTM:Isoform 2 undergoes tyrosine phosphorylation upon T-cell receptor (TCR) stimulation. This phosphorylation has not been confirmed by other group.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the eukaryotic RPA34 RNA polymerase subunit family.,subcellular location:Found at the fibrillar centers of the nucleolus in interphase and during cell division it is localized to the nucleolus organizer regions of the chromosomes.,subunit:Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits. Interacts with TAF1A thereby associates with the SL1 complex. Interacts with UBTF. Interacts with POLR1E/PRAF1 through its N-terminal region (By similarity). Isoform 2 interacts with CD3E.,
Gene Name: CD3EAP
Protein Name: DNA-directed RNA polymerase I subunit RPA34
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分子量
- 54 kDa
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基因ID
- 10849
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OMIM
- 107325
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UniProt
- O15446
抗原
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