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DMGDH 抗体 (AA 817-866)

The 兔 多克隆 anti-DMGDH antibody is suitable to detect DMGDH in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN1534834
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for DMGDH 抗体 (AA 817-866) (ABIN1534834)

抗原

See all DMGDH 抗体
DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

适用

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人, 小鼠, 大鼠

宿主

  • 31
兔

克隆类型

  • 31
多克隆

标记

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  • 3
  • 2
  • 2
  • 1
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This DMGDH antibody is un-conjugated

应用范围

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  • 16
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    AA 817-866

    原理

    DMGDH Antibody

    特异性

    DMGDH Polyclonal Antibody detects endogenous levels of DMGDH protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human DMGDH. AA range:817-866

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

    别名

    DMGDH

    背景

    Synonyms: DMGDH, Dimethylglycine dehydrogenase, mitochondrial, ME2GLYDH

    Background: This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

    Gene Name: DMGDH

    Protein Name: Dimethylglycine dehydrogenase mitochondrial

    分子量

    96 kDa

    基因ID

    29958

    OMIM

    605849

    UniProt

    Q9UI17
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