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DPYSL4 抗体 (AA 91-140)

The 兔 多克隆 anti-DPYSL4 antibody (ABIN1534832) specifically detects DPYSL4 in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1534832
发货至: 中国
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Quick Overview for DPYSL4 抗体 (AA 91-140) (ABIN1534832)

抗原

See all DPYSL4 抗体
DPYSL4 (Dihydropyrimidinase-Like 4 (DPYSL4))

适用

  • 31
  • 13
  • 13
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 27
  • 4
兔

克隆类型

  • 27
  • 4
多克隆

标记

  • 19
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DPYSL4 antibody is un-conjugated

应用范围

  • 19
  • 12
  • 4
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 91-140

    原理

    CRMP-3 Antibody

    特异性

    CRMP-3 Polyclonal Antibody detects endogenous levels of CRMP-3 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human DPYSL4. AA range:91-140

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    DPYSL4 (Dihydropyrimidinase-Like 4 (DPYSL4))

    别名

    DPYSL4

    背景

    Synonyms: DPYSL4, CRMP3, ULIP4, Dihydropyrimidinase-related protein 4, DRP-4, Collapsin response mediator protein 3, CRMP-3, UNC33-like phosphoprotein 4, ULIP-4

    Background: disease:Antibodies against post-translationally modified DPYSL4, also called anti-CV2 autoantibodies, are present in sera from patients with paraneoplastic neurological diseases (PND). PND are disorders of the nervous system associated with various systemic cancers which are not a direct result of the tumor mass or metastasis, but attributed to remote effects of the cancer.,function:Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.,subunit:Homotetramer, and heterotetramer with CRMP1, DPYSL2, DPYSL3 or DPYSL5. Interacts with PLEXA1.,

    Gene Name: DPYSL4

    Protein Name: Dihydropyrimidinase-related protein 4

    分子量

    61 kDa

    基因ID

    10570

    OMIM

    608407

    UniProt

    O14531
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