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DHRS4 抗体 (AA 191-240)

The 兔 多克隆 anti-DHRS4 antibody (ABIN1534826) specifically detects DHRS4 in WB, IHC, ELISA 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1534826
发货至: 中国
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Quick Overview for DHRS4 抗体 (AA 191-240) (ABIN1534826)

抗原

See all DHRS4 抗体
DHRS4 (Dehydrogenase/reductase (SDR Family) Member 4 (DHRS4))

适用

  • 33
  • 6
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 31
  • 2
兔

克隆类型

  • 33
多克隆

标记

  • 12
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DHRS4 antibody is un-conjugated

应用范围

  • 26
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 191-240

    原理

    DHRS4 Antibody

    特异性

    DHRS4 Polyclonal Antibody detects endogenous levels of DHRS4 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human DHRS4. AA range:191-240

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    DHRS4 (Dehydrogenase/reductase (SDR Family) Member 4 (DHRS4))

    别名

    DHRS4

    背景

    Synonyms: DHRS4, Dehydrogenase/reductase SDR family member 4, NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase, CR, PHCR, NADPH-dependent retinol dehydrogenase/reductase, NRDR, humNRDR, Peroxisomal short-chain alcohol dehydrogenase, PSCD

    Background: catalytic activity:R-CHOH-R' + NADP(+) = R-CO-R' + NADPH.,function:Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones.,miscellaneous:Inhibited by kaempferol, quercetin, genistein and myristic acid.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,subcellular location:Isoform 1 is peroxisomal, while isoform 4 is not.,subunit:Homotetramer.,tissue specificity:Isoform 1 is predominantly expressed in normal cervix (at protein level). Isoform 4 is expressed in some neoplastic cervical tissues, but not in normal cervix (at protein level). Isoforms 5 and 6 are expressed in a few neoplastic cervical tissues.,

    Gene Name: DHRS4

    Protein Name: Dehydrogenase/reductase SDR family member 4

    分子量

    27 kDa

    基因ID

    10901

    OMIM

    611596

    UniProt

    Q9BTZ2
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