DOCK1 抗体 (AA 1661-1710)
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北京 101111
Quick Overview for DOCK1 抗体 (AA 1661-1710) (ABIN1534823)
抗原
See all DOCK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1661-1710
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原理
- DOCK 180 Antibody
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特异性
- DOCK 180 Polyclonal Antibody detects endogenous levels of DOCK 180 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human DOCK1. AA range:1661-1710
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))
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别名
- DOCK1
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背景
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Synonyms: DOCK1, Dedicator of cytokinesis protein 1, 180 kDa protein downstream of CRK, DOCK180
Background: This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014],
Gene Name: DOCK1
Protein Name: Dedicator of cytokinesis protein 1
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分子量
- 215 kDa
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基因ID
- 1793
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OMIM
- 601403
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UniProt
- Q14185
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途径
- Signaling of Hepatocyte Growth Factor Receptor
抗原
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