Claudin 19 抗体 (AA 81-130)
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北京 101111
Quick Overview for Claudin 19 抗体 (AA 81-130) (ABIN1534781)
抗原
See all Claudin 19 (CLDN19) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 81-130
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原理
- Claudin-19 Antibody
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特异性
- Claudin-19 Polyclonal Antibody detects endogenous levels of Claudin-19 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human CLDN19. AA range:81-130
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Claudin 19 (CLDN19)
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别名
- CLDN19
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背景
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Synonyms: CLDN19, Claudin-19
Background: The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010],
Gene Name: CLDN19
Protein Name: Claudin-19
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分子量
- 23 kDa
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基因ID
- 149461
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OMIM
- 610036
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UniProt
- Q8N6F1
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途径
- Cell-Cell Junction Organization, Hepatitis C
抗原
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