CDC42EP5 抗体 (AA 1-50)
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北京 101111
Quick Overview for CDC42EP5 抗体 (AA 1-50) (ABIN1534743)
抗原
See all CDC42EP5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-50
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原理
- Cdc42EP5 Antibody
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特异性
- Cdc42EP5 Polyclonal Antibody detects endogenous levels of Cdc42EP5 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human BORG3. AA range:1-50
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CDC42EP5 (CDC42 Effector Protein (Rho GTPase Binding) 5 (CDC42EP5))
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别名
- BORG3
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背景
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Synonyms: CDC42EP5, BORG3, CEP5, Cdc42 effector protein 5, Binder of Rho GTPases 3
Background: Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins.The protein encoded byThis gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts [provided by RefSeq, Jul 2013],
Gene Name: CDC42EP5
Protein Name: Cdc42 effector protein 5
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分子量
- 15 kDa
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基因ID
- 148170
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OMIM
- 609171
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UniProt
- Q6NZY7
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途径
- Regulation of Actin Filament Polymerization
抗原
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