CPN1 抗体 (AA 409-458)
Our Local Distributor
北京 101111
Quick Overview for CPN1 抗体 (AA 409-458) (ABIN1534736)
抗原
See all CPN1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 409-458
-
原理
- CPN cat Antibody
-
特异性
- CPN cat Polyclonal Antibody detects endogenous levels of CPN cat protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human CPN1. AA range:409-458
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- CPN1 (Carboxypeptidase N Subunit 1 (CPN1))
-
别名
- CPN1
-
背景
-
Synonyms: CPN1, ACBP, Carboxypeptidase N catalytic chain, CPN, Anaphylatoxin inactivator, Arginine carboxypeptidase, Carboxypeptidase N polypeptide 1, Carboxypeptidase N small subunit, Kininase-1, Lysine carboxypeptidase, Plasma carboxypeptidase B, S
Background: Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits,This gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq, Jul 2008],
Gene Name: CPN1
Protein Name: Carboxypeptidase N catalytic chain
-
分子量
- 52 kDa
-
基因ID
- 1369
-
OMIM
- 603103
-
UniProt
- P15169
-
途径
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process
抗原
-