CPB2 抗体 (AA 321-370)
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北京 101111
Quick Overview for CPB2 抗体 (AA 321-370) (ABIN1534733)
抗原
See all CPB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 321-370
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原理
- TAFI Antibody
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特异性
- TAFI Polyclonal Antibody detects endogenous levels of TAFI protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human CPB2. AA range:321-370
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))
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别名
- CPB2
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背景
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Synonyms: CPB2, Carboxypeptidase B2, Carboxypeptidase U, CPU, Plasma carboxypeptidase B, pCPB, Thrombin-activable fibrinolysis inhibitor, TAFI
Background: Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues).The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],
Gene Name: CPB2
Protein Name: Carboxypeptidase B2
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分子量
- 48 kDa
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基因ID
- 1361
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OMIM
- 603101
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UniProt
- Q96IY4
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途径
- Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis
抗原
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