BAIAP2L1 抗体 (AA 111-160)
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Quick Overview for BAIAP2L1 抗体 (AA 111-160) (ABIN1534702)
抗原
See all BAIAP2L1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 111-160
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原理
- IRTKS Antibody
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特异性
- IRTKS Polyclonal Antibody detects endogenous levels of IRTKS protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human BAIAP2L1. AA range:111-160
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- BAIAP2L1 (BAI1-Associated Protein 2-Like-1 (BAIAP2L1))
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别名
- BAIAP2L1
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背景
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Synonyms: BAIAP2L1, IRTKS, Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1, BAI1-associated protein 2-like protein 1, Insulin receptor tyrosine kinase substrate
Background: This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain.The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal fo
Gene Name: BAIAP2L1
Protein Name: Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1
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分子量
- 56 kDa
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基因ID
- 55971
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OMIM
- 611877
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UniProt
- Q9UHR4
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途径
- Regulation of Actin Filament Polymerization
抗原
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