LAMA3 抗体 (AA 2571-2620)
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Quick Overview for LAMA3 抗体 (AA 2571-2620) (ABIN1534453)
抗原
See all LAMA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2571-2620
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原理
- Laminin α-3 Antibody
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特异性
- Laminin α-3 Polyclonal Antibody detects endogenous levels of Laminin α-3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human LAMA3. AA range:2571-2620
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- LAMA3 (Laminin, alpha 3 (LAMA3))
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别名
- LAMA3
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背景
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Synonyms: LAMA3, LAMNA, Laminin subunit alpha-3, Epiligrin 170 kDa subunit, E170, Epiligrin subunit alpha, Kalinin subunit alpha, Laminin-5 subunit alpha, Laminin-6 subunit alpha, Laminin-7 subunit alpha, Nicein subunit alpha
Background: The protein encoded by this gene belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction.This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants. [provided by RefSeq, Dec 2014],
Gene Name: LAMA3
Protein Name: Laminin subunit alpha-3
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分子量
- 189 kDa
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基因ID
- 3909
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OMIM
- 226700
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UniProt
- Q16787
抗原
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