Laminin 抗体 (AA 2011-2060)
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Quick Overview for Laminin 抗体 (AA 2011-2060) (ABIN1534452)
抗原
See all Laminin (LAMA2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2011-2060
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原理
- Laminin α-2 Antibody
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特异性
- Laminin α-2 Polyclonal Antibody detects endogenous levels of Laminin α-2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human LAMA2. AA range:2011-2060
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Laminin (LAMA2) (Laminin, alpha 2 (LAMA2))
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别名
- LAMA2
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背景
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Synonyms: LAMA2, LAMM, Laminin subunit alpha-2, Laminin M chain, Laminin-12 subunit alpha, Laminin-2 subunit alpha, Laminin-4 subunit alpha, Merosin heavy chain
Background: Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule.This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Jul 2008],
Gene Name: LAMA2
Protein Name: Laminin subunit alpha-2
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分子量
- 342 kDa
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基因ID
- 3908
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OMIM
- 156225
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UniProt
- P24043
抗原
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