CDCA3 抗体 (AA 219-268)
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Quick Overview for CDCA3 抗体 (AA 219-268) (ABIN1534322)
抗原
See all CDCA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 219-268
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原理
- CdcA3 Antibody
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特异性
- CdcA3 Polyclonal Antibody detects endogenous levels of CdcA3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human CDCA3. AA range:219-268
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CDCA3 (Cell Division Cycle Associated 3 (CDCA3))
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别名
- CDCA3
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背景
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Synonyms: CDCA3, C8, GRCC8, TOME1, Cell division cycle-associated protein 3, Gene-rich cluster protein C8, Trigger of mitotic entry protein 1, TOME-1
Background: domain:The KEN box is required for the association with the APC/C-Cdh1 complex.,function:F-box-like protein which is required for entry into mitosis. Acts by participating to E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase.,pathway:Protein modification, protein ubiquitination.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,PTM:Ubiquitinated and degraded by the APC/C-Cdh1 complex.,subunit:Interacts with SKP1A. Part of a SCF (SKP1-cullin-F-box) protein ligase complex.,
Gene Name: CDCA3
Protein Name: Cell division cycle-associated protein 3
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分子量
- 28 kDa
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基因ID
- 83461
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OMIM
- 607749
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UniProt
- Q99618
抗原
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