CDC6 抗体 (AA 491-540)
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北京 101111
Quick Overview for CDC6 抗体 (AA 491-540) (ABIN1534320)
抗原
See all CDC6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 491-540
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原理
- Cdc6 Antibody
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特异性
- Cdc6 Polyclonal Antibody detects endogenous levels of Cdc6 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human CDC6. AA range:491-540
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))
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别名
- CDC6
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背景
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Synonyms: CDC6, CDC18L, Cell division control protein 6 homolog, CDC6-related protein, Cdc18-related protein, HsCdc18, p62(cdc6), HsCDC6
Background: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008],
Gene Name: CDC6
Protein Name: Cell division control protein 6 homolog
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分子量
- 62 kDa
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基因ID
- 990
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OMIM
- 602627
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UniProt
- Q99741
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途径
- DNA Replication, Synthesis of DNA
抗原
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