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P-Cadherin 抗体 (AA 51-100)

The 兔 多克隆 anti-P-Cadherin antibody (ABIN1534295) specifically detects P-Cadherin in WB, IHC, ELISA 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1534295
发货至: 中国
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Quick Overview for P-Cadherin 抗体 (AA 51-100) (ABIN1534295)

抗原

See all P-Cadherin (CDH3) 抗体
P-Cadherin (CDH3)

适用

  • 172
  • 33
  • 7
  • 1
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人, 小鼠, 大鼠

宿主

  • 131
  • 46
  • 6
  • 2
兔

克隆类型

  • 129
  • 51
  • 3
多克隆

标记

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This P-Cadherin antibody is un-conjugated

应用范围

  • 146
  • 68
  • 63
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  • 54
  • 46
  • 14
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  • 10
  • 5
  • 3
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 26
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    • 9
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    • 8
    • 5
    • 5
    • 4
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    • 1
    • 1
    • 1
    • 1
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    AA 51-100

    原理

    P-cadherin Antibody

    特异性

    P-cadherin Polyclonal Antibody detects endogenous levels of P-cadherin protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human CDH3. AA range:51-100

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    P-Cadherin (CDH3)

    别名

    CDH3

    背景

    Synonyms: CDH3, CDHP, Cadherin-3, Placental cadherin, P-cadherin

    Background: This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015],

    Gene Name: CDH3

    Protein Name: Cadherin-3

    分子量

    91 kDa

    基因ID

    1001

    OMIM

    114021

    UniProt

    P22223
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