LI Cadherin 抗体 (AA 341-390)
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北京 101111
Quick Overview for LI Cadherin 抗体 (AA 341-390) (ABIN1534286)
抗原
See all LI Cadherin 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 341-390
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原理
- LI-cadherin Antibody
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特异性
- LI-cadherin Polyclonal Antibody detects endogenous levels of LI-cadherin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human CDH17. AA range:341-390
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- LI Cadherin
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别名
- CDH17
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背景
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Synonyms: CDH17, Cadherin-17, Intestinal peptide-associated transporter HPT-1, Liver-intestine cadherin, LI-cadherin
Background: This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009],
Gene Name: CDH17
Protein Name: Cadherin-17
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分子量
- 92 kDa
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基因ID
- 1015
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OMIM
- 603017
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UniProt
- Q12864
抗原
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