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CABLES1 抗体 (AA 561-610)

The 兔 多克隆 anti-CABLES1 antibody is suitable to detect CABLES1 in samples from 人 和 小鼠. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN1534279
发货至: 中国
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Quick Overview for CABLES1 抗体 (AA 561-610) (ABIN1534279)

抗原

See all CABLES1 抗体
CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))

适用

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  • 19
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  • 3
  • 3
  • 2
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  • 1
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  • 1
人, 小鼠

宿主

  • 24
  • 3
兔

克隆类型

  • 26
  • 1
多克隆

标记

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  • 1
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This CABLES1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 561-610

    原理

    Cables1 Antibody

    特异性

    Cables1 Polyclonal Antibody detects endogenous levels of Cables1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Ik3-1. AA range:561-610

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))

    别名

    Ik3-1

    背景

    Synonyms: CABLES1, CABLES, CDK5 and ABL1 enzyme substrate 1, Interactor with CDK3 1, Ik3-1

    Background: This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],

    Gene Name: CABLES1

    Protein Name: CDK5 and ABL1 enzyme substrate 1

    分子量

    67 kDa

    基因ID

    91768

    OMIM

    609194

    UniProt

    Q8TDN4
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