CABLES1 抗体 (AA 561-610)
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北京 101111
Quick Overview for CABLES1 抗体 (AA 561-610) (ABIN1534279)
抗原
See all CABLES1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 561-610
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原理
- Cables1 Antibody
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特异性
- Cables1 Polyclonal Antibody detects endogenous levels of Cables1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Ik3-1. AA range:561-610
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))
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别名
- Ik3-1
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背景
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Synonyms: CABLES1, CABLES, CDK5 and ABL1 enzyme substrate 1, Interactor with CDK3 1, Ik3-1
Background: This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],
Gene Name: CABLES1
Protein Name: CDK5 and ABL1 enzyme substrate 1
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分子量
- 67 kDa
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基因ID
- 91768
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OMIM
- 609194
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UniProt
- Q8TDN4
抗原
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