ADD3 抗体 (AA 431-480)
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北京 101111
Quick Overview for ADD3 抗体 (AA 431-480) (ABIN1534259)
抗原
See all ADD3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 431-480
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原理
- Adducin γ Antibody
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特异性
- Adducin γ Polyclonal Antibody detects endogenous levels of Adducin γ protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human ADD3. AA range:431-480
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ADD3 (Adducin 3 (Gamma) (ADD3))
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别名
- ADD3
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背景
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Synonyms: ADD3, ADDL, Gamma-adducin, Adducin-like protein 70
Background: adducin 3(ADD3) Homo sapiens Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region i
Gene Name: ADD3
Protein Name: Gamma-adducin
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分子量
- 79 kDa
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基因ID
- 120
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OMIM
- 601568
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UniProt
- Q9UEY8
抗原
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