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ADD3 抗体 (AA 431-480)

The 兔 多克隆 anti-ADD3 antibody (ABIN1534259) specifically detects ADD3 in WB, ELISA, IF 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1534259
发货至: 中国
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Quick Overview for ADD3 抗体 (AA 431-480) (ABIN1534259)

抗原

See all ADD3 抗体
ADD3 (Adducin 3 (Gamma) (ADD3))

适用

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人, 小鼠, 大鼠

宿主

  • 34
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兔

克隆类型

  • 35
多克隆

标记

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This ADD3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 431-480

    原理

    Adducin γ Antibody

    特异性

    Adducin γ Polyclonal Antibody detects endogenous levels of Adducin γ protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human ADD3. AA range:431-480

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    ADD3 (Adducin 3 (Gamma) (ADD3))

    别名

    ADD3

    背景

    Synonyms: ADD3, ADDL, Gamma-adducin, Adducin-like protein 70

    Background: adducin 3(ADD3) Homo sapiens Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region i

    Gene Name: ADD3

    Protein Name: Gamma-adducin

    分子量

    79 kDa

    基因ID

    120

    OMIM

    601568

    UniProt

    Q9UEY8
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