YWHAE 抗体 (AA 206-255)
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Quick Overview for YWHAE 抗体 (AA 206-255) (ABIN1534233)
抗原
See all YWHAE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 206-255
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原理
- 14-3-3 ε Antibody
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特异性
- 14-3-3 ε Polyclonal Antibody detects endogenous levels of 14-3-3 ε protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human 14-3-3 epsilon. AA range:206-255
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- YWHAE (14-3-3 epsilon (YWHAE))
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别名
- 14-3-3 epsilon
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背景
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Synonyms: YWHAE, 14-3-3 protein epsilon, 14-3-3E
Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100 % identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008],
Gene Name: YWHAE
Protein Name: 14-3-3 protein epsilon
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分子量
- 29 kDa
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基因ID
- 7531
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OMIM
- 605066
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UniProt
- P62258
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途径
- Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase
抗原
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