JIP3 抗体 (AA 621-670)
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Quick Overview for JIP3 抗体 (AA 621-670) (ABIN1534197)
抗原
See all JIP3 (MAPK8IP3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 621-670
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原理
- JIP-3 Antibody
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特异性
- JIP-3 Polyclonal Antibody detects endogenous levels of JIP-3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human JIP3. AA range:621-670
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- JIP3 (MAPK8IP3) (Mitogen-Activated Protein Kinase 8 Interacting Protein 3 (MAPK8IP3))
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别名
- JIP3
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背景
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Synonyms: MAPK8IP3, JIP3, KIAA1066, C-Jun-amino-terminal kinase-interacting protein 3, JIP-3, JNK-interacting protein 3, JNK MAP kinase scaffold protein 3, Mitogen-activated protein kinase 8-interacting protein 3
Background: The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008],
Gene Name: MAPK8IP3
Protein Name: C-Jun-amino-terminal kinase-interacting protein 3
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分子量
- 147 kDa
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基因ID
- 23162
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OMIM
- 605431
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UniProt
- Q9UPT6
抗原
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