TCFL5 抗体 (AA 311-360)
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北京 101111
Quick Overview for TCFL5 抗体 (AA 311-360) (ABIN1534189)
抗原
See all TCFL5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 311-360
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原理
- TCFL5 Antibody
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特异性
- TCFL5 Polyclonal Antibody detects endogenous levels of TCFL5 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human TCFL5. AA range:311-360
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TCFL5 (Transcription Factor-Like 5 (Basic Helix-Loop-Helix) (TCFL5))
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别名
- TCFL5
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背景
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Synonyms: TCFL5, CHA, E2BP1, Transcription factor-like 5 protein, Cha transcription factor, HPV-16 E2-binding protein 1, E2BP-1
Background: developmental stage:Isoform 3 is specifically expressed in primary spermatocytes at the pachytene stage, but not those at leptonema stage. Not expressed in other testicular cells, including spermatogonia located in the basal compartment of the seminiferous tubule or spermatids.,disease:Antibodies against TCFL5 are present in sera from patients with Chagas' disease, an autoimmune disease caused by Trypanosoma cruzi. Two different epitopes that mimic Trypanosoma cruzi antigens have been identified: R1 and R3 epitopes, which are recognized by T- and B-cells, respectively.,function:Putative transcription factor. Isoform 3 may play a role in early spermatogenesis.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,tissue specificity:Isoform 3 is testis specific. Isoform 2 is pancreas specific.,
Gene Name: TCFL5
Protein Name: Transcription factor-like 5 protein
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分子量
- 48 kDa
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基因ID
- 10732
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OMIM
- 604745
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UniProt
- Q9UL49
抗原
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